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Abstract

FINCTOR BNCT FUND SP



As an emerging therapy in the market, BNCT has received attention from more and more medical institutions across the globe with its low cost, high response rate, short treatment time and non-intrusive features.

The research bottleneck remained until Dr. GP Yeh, an American born Chinese expert in high-energy physics, developed the accelerator technology for producing adequate number of neutrons by building on the proton technology in the National Fermi Accelerator Laboratory (FERMILAB) in the United States, which marked a major stride in the development of BNCT.

Based on the German National Innovation Model and ecosystem network investment strategy as the core investment philosophy, we have launched the SP to realize the value investments in the BNCT industry.

To accomplish the abovementioned investment objectives, we comply with the regulations of relevant supervisory authorities by setting up a fund offering and management framework in compliance with Economic Substance Act, international anti-money laundering regulations and fund governance standards for safeguarding the interests of fund investors and building the bridge between market capital and development of BCNT industry to realize the goal of industrialization and strive for a higher return for the investors.

The total size of this fund is 200 million US dollars and the first fundraising to reach an amount of 80 million US dollars is under way.

Why Are We Launching the SP?

FINCTOR BNCT FUND SP



  • The main promoter of this fund Mr. Wu, Chen-yu (Galahad Wu), worked as the Special Assistant to CEO of Dr GP Yeh International Affairs Office in 2009. Based in Bejing, he was responsible for assisting with international exchanges on the accelerator technology.

  • 2020, after the successful application of the accelerator technology in producing neutron beams, Mr. Wu heeded the call of Dr. Yeh and started the BNCT Industrial Development Fund.

  • Under the framework of cooperation with the GP Yeh Foundation, we focus on investing in the upstream and downstream businesses with our unique investment strategy to complete our presence in the industry and speed up the development of BNCT industry.

SP Operational Goals

FINCTOR BNCT FUND SP



Respect for life and pursuit of improvement of medical standards.


Lowering of cancer treatment threshold and increase of chance of survival of cancer patients.


Promotion of development and industrialization of cancer treatment technologies.



Pursuit of increase of investment profits though value investment strategies.

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SP Investment Period

FINCTOR BNCT FUND SP


Percentage Distribution of SP Investment

FINCTOR BNCT FUND SP


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Value of BNCT

FINCTOR BNCT FUND SP


  • For investors, BNCT will be new technology which has a profound on the development of medication. The advent of BNCT, however, does not entail abandonment of all other cancer therapies. In fact, BNCT can be coupled with other treatments to provide the patients with better medication quality and increase the response rate.

  • As compared with other major traditional cancer treating methods, immunotherapy and radioactive therapy, the advantages of BNCT are manifest in the three aspects:

Low medication cost Low equipment cost No need for hospitalization
The cost of treatment is lower than current target drugs and immunotherapy. More accurate than proton therapy or heavy particle therapy and lower equipment cost. In contrast with 15-day hospital observation stay for patients receiving general cancer treatments, European and American patients do not need to stay in hospital for observation after BNCT.


Market hypothesis for industrial development

FINCTOR BNCT FUND SP



“After decades of development, there have been nearly 20,000 theses and more than 5,000 treatment cases around the world, proving the effectiveness of BNCT.”


The key points of BNCT market development hypothesis are as follows:

  • Cancer remains the top death cause for mankind.
  • There is still room for new therapy in cancer treatment which has an annual market size of 1 trillion dollars.
  • A new investment method combining market capital with a national innovation model can bring about excess returns.
  • The industry supply system invested by the SP can bring updates and iterations to the existing supply chain.
  • A new industrial supply system relies on the establishment of key core businesses and key businesses.

There have been nearly
20,000
Theses
Over
5,000
Treatment Cases
The development of
Accelerator
Technology
Suitable for intro of
Low
Medication Cost

People with Cancer is in Rapid Growth

FINCTOR BNCT FUND SP


Global new cancer cases
increase yearly

22

Million People

IARC (~2032 est.)
The global
deaths of cancer9600

Thousand Cases

WHO (2018)
Average global cancer
mortality48

%

WHO (2018)
Cancer deaths
will occur in Asia over50

%

WHO (2018)
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BNCT
The new binary cancer treatment

FINCTOR BNCT FUND SPC



Boron neutron capture therapy (BNCT) is a binary cancer treatment. In cancer cells, when an atom absorbs low-energy thermal neutrons, a cytotoxicity event occurs.


This remarkable treatment was proposed by GORDAN L. LOCHER in 1936, shortly after the discovery of neutrons, and since 1950, clinical and chemical research related to BNCT has seen progress.Boron compounds are easily incorporated into organic structures, and their chemical properties have been extensively studied。This is an ideal treatment as it can kill cancer cells while preserving healthy ones.

How BNCT Works?

FINCTOR BNCT FUND SPC



BNCT, like proton and heavy particle therapy, is a type of radiotherapy and is also a developing cancer treatment method. It works by using boron to absorb neutrons and then split them into lithium and alpha particles to treat cancer. The range of damage to cancer cells is only 5-10μm without affecting surrounding healthy cells.

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Scale of Cancer Treatment Market

FINCTOR BNCT FUND SP


New anticancer compounds over

710

kinds in developing or clinical trial

Estimated by NTI Japan
(2019.07)
Global cancer therapy market size1

Trillion dollars

Estimated by NTI Japan
(2019)
Global radiation equipment market size93

100 million

Estimated by TRI
(~2024 est.)
The global medical equipment market5776

100 million

Estimated by TRI (~2023 est.)
(~2023 est.)

The above information shows that there are still opportunities for the development of new therapies in the huge cancer treatment market. Humans have not yet found a truly effective way to fight cancer, and physics-based radiotherapy is also developing rapidly.

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The Steps of BNCT

FINCTOR BNCT FUND SPC



For the steps of modern boron neutron capture treatment

F18-BPA-PET is usually used to confirm the extent of tumor absorption of BPA before treatment, that is, calculate the ratio of tumor/normal tissue (T/N) BPA concentration.
The patient is simulated by computer tomography and the images are transmitted to the software to calculate the dose distribution.。
After the prescribed dose and treatment plan are confirmed, the patient is injected with BPA for several hours before receiving neutron irradiation.

The types of cancers that have been clinically effective by BNCT treatment

FINCTOR BNCT FUND SP




BNCT, a cancer treatment method booming worldwide, can currently be applied to at least 12 cancer treatments. With the continuous investment of relevant medical and research institutions around the world, it is expected that it will gradually be applied to more kinds of cancer treatments. The types of cancers that have been clinically effective are as follows:



01.Brain tumors 02.Colorectal tumors 03.Malignant meningioma 04.Liver metastasis
05.Head and neck tumors 06.Genital tumors 07.Glioblastoma 08.Breast cancer
09.Melanoma 10.Radio-resistant tumors 11.Children brain tumors 12.Spinal glioma